Inject one marijuanas
A new study found that injecting pure THC triggered schizophrenia-like behaviors in subjects. But, uh, does anyone actually consume weed this way?
The study, conducted by schizophrenia researchers at the Veterans Affairs Healthcare System in Connecticut, and recently published in Neuropsychopharmacology, involved shooting up 22 healthy individuals with 2.5mg THC, 5mg THC, or a placebo (0mg THC). The subjects had previously been “exposed” to cannabis, but none had been diagnosed with cannabis use disorder.
After three separate days of mainlining pure THC, the subjects reported experiencing schizophrenia-like symptoms, increased anxiety, altered perceptions, euphoria, and a host of memory and speech issues. Their blood also showed increased levels of cortisol, the primary stress hormone. Not surprisingly, the researchers concluded that THC produces psychotic behaviors, and more studies are needed to see how cannabinoid receptors may contribute to psychotic disorders.
Usually when we see anything about injecting THC or “marijuanas,” it comes from satirical social media accounts that claim shooting up weed can cause everything from suddenly turning someone gay to spontaneous death (again, these are memes). But intravenous administration of THC is a standard (though not terribly common) practice in cannabis studies, since it gives researchers precise control over dosing. The only problem with this study and others like it is that no one actually injects pure THC. There’s a reason why most consumers prefer to smoke or vape cannabis, after all.
When someone smokes, let’s say, a one-gram joint rolled with weed containing 25 percent THC, that joint contains, roughly, 250mg of THCA, the form of THC that doesn’t get anyone high. Heat converts some THCA into THC — the stuff that gets people lit — but only some THCA turns into the psychoactive form. The average time that heat is applied to the joint isn’t long enough to convert all of the THCA to THC. Furthermore, a bunch of converted THC gets lost in the smoke that wafts from the joint, and even more THC gets stuck in the ash.
So, by the end of it, even if just one person smoked that entire 1-gram joint to the face, they’re only getting a small fraction of that potential 250mg THC, not to mention a cornucopia of other compounds such as other cannabinoids, terpenes, flavonoids, and polyphenols — which all may interact with our brain’s cannabinoid receptors, dulling the negative effects of THC.
In other words, shooting someone up with 2.5mg or 5mg pure THC is kind of a lot, especially for non-stoners, which this study focused on.
In addition to there being next-to-no people who shoot up THC distillate or diamonds on a regular basis, no one shoots up actual weed, either. Back in the ‘70s and ‘80s, some idiots tried that, and they developed what’s called “intravenously injected marijuana disorder.” Basically, folks would boil weed buds into a “broth,” pull that filtered broth up into a syringe, then inject it. Rather than getting lit, they got sick AF instead, which included bouts of vomiting, intense muscle pains, and serious heart problems.
Here’s the thing about IV marijuana disorder, too: There are practically no new case studies on it after 1986, suggesting that only a handful of people did it back in the day. Why? Obviously, it sucks, and it’s potentially life-threatening. Which is why, today and in the past, folks have stuck to puffing their pot.
Does this mean that everything about the VA study is bogus? Not entirely. We know that the endocannabinoid system plays a role in some mental disorders, and cannabis use can aggravate some psychotic symptoms in people particularly prone to them. However, many cannabis patients consume weed to alleviate symptoms of their personality or mood disorders, too, so the issue isn’t black-and-white, nor is it clear-cut.
Oh, and in case if you’re wondering if you can snort weed, yeah, technically, that’s possible. But you’ll end up blowing pot-snot all day and never catching a buzz.
Can you "inject marijuanas," as the satirical memes suggest? Yes, but it’s a really, really stupid thing to do, according to a new study.
Faces of Marijuana
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Faces of Marijuana, also known as “Faces of Pot,” is a series of images that parody hyperbolic anti-drug PSA posters. The pictures are typically edited to show unrealistic or absurd consequences of smoking marijuana, many of which use a similar format to the Faces of Meth  mug shot website and X Isn’t Normal, But on Meth it Is parody images.
While parodies of anti-marijuana propaganda have existed for many years since the beginning of War on Drugs in the 1970s, the earliest known “Faces of Marijuana” instance was uploaded by YouTuber pianoflames on February 15th, 2011, which featured several a slideshow of satirical before-and-after photographs of people that purportedly consumed too much marijuana (shown below). Within the next two years, the video accumulated over 13,000 up votes and 140 comments.
On May 9th, 2012, the Cheezburger site FAIL Blog  published a before-and-after image showing a black man becoming a white man after “2 hits” of marijuana (shown below).
On October 15th, Redditor ReAzem submitted a parody of anti-marijuana PSA poster to the /r/4chan  subreddit, which urged readers to avoid injecting marijuana by showing mug shots from the Faces of Meth website (shown below, left). Within three months, the post received over 6,300 up votes and 200 comments. On November 4th, FunnyJunk  user onlyfornsfwhaha submitted another parody poster featuring a man who appears to have overdosed on heroin with the caption “Marijuana / What will your mother say when she finds your corpse?” (shown below, right). Within the next three months, the post received over 54,000 views, 1,600 up votes and 260 comments.
On November 29th, Redditor xerim submitted an image to the marijuana enthusiast subreddit /r/trees,  featuring a white man turning into a black man after consuming marijuana (shown below, left). On December 13th, the same image was tweeted by the @ConcernedMom420 Twitter account. Within two months, the post received over 1,400 up votes and 45 comments. On January 3rd, 2013, the “Faces of Marijuana” Facebook  page was launched, featuring notable examples of parody anti-marijuana images. On the following day, the Colorado news blog Westword  published several “Faces of Pot” images, including a photo of a pit bull turning into Stoner Dog (shown below, right).
Faces of Marijuana, also known as “Faces of Pot,” is a series of images that parody hyperbolic anti-drug PSA posters. The pictures are typically edited to show unrealistic or absurd consequences of smoking marijuana, many of which use a similar format to the Faces of Meth mug shot website and X Isn’t Normal, But on Meth it Is parody images.