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Duke genetics

In PNAS this week: genetic and epigenetic variation in individuals with diabetic kidney disease, spontaneous genetic alterations in Saccharomyces cerevisiae, and more.

Inflammatix Moving Into Coronavirus Test Market With Gene Expression Host Response Platform

Inflammatix said that if its test obtains Emergency Use Authorization next year, clinicians will be able to better gauge the severity of a COVID-19 patient’s infection.

SARS-CoV-2 Result of Bat, Pangolin Virus Recombination, Purifying Selection, Study Suggests

The ancestor of a bat coronavirus may have obtained a receptor binding motif found among pangolin coronaviruses through a recombination event.

Chan Zuckerberg Initiative Awards $3.8M in Grants for Open-Source Biomedical Software Projects

The funding marks the second cycle of CZI’s Essential Open Source Software program, which awards between $50,000 and $250,000 in total costs per project.

Cell Studies on Antiviral CRISPR Approach, Obesity and Pancreatic Cancer, Ancient Andeans

In Cell this week: strategy for prophylactic antiviral CRISPR in human cells; influence of obesity, genetics, and hormone signaling on pancreatic ductal adenocarcinoma; and more.

NIH Awards $102.5M for Antibacterial Resistance Research, Dx Development

The seven-year grant renews funding for the Antibacterial Resistance Leadership Group, led by Duke University and UCSF, with $15 million in 2020.

Conditions to Be Removed

Retraction Watch reports that the National Institutes of Health plans to remove conditions it placed on Duke University in 2018 following instances of research misconduct.

Many Dollar Bills There

According to the Associated Press, three universities and a healthcare institution are sharing a gift of $1 billion.

Not a Dime Again

A former Duke University biologist who was found to have fabricated data in 39 papers has been banned from receiving federal funding.

Dart-seq Leads New Methods to Sequence Transcriptome Methylation Patterns

A new sequencing-based method developed by Duke University’s Kate Meyer is one of several that can detect RNA methylation without the use of antibodies.

News and reporting on Duke from GenomeWeb Genetics & Genomics.

Clinical Cancer Genetics

Cancer Genetics

Duke’s hereditary cancer experts offer genetic testing and genetic counseling to people diagnosed with cancer, as well as people who may be at risk of developing cancer. Genetic counselors work closely with oncologists who are trained to diagnose and treat hereditary cancers, comprising five to 10 percent of all cancers. Genetic counseling can help guide treatment. Experts can clarify risks and offer expert counseling. Counselors help patients make informed decisions about treatment options and lifestyle changes.

If cancer runs in a family, members may consider genetic testing to determine cancer risk. If a patient has already been diagnosed breast cancer, ovarian cancer, or colon cancer, knowing whether this cancer is inherited can direct treatment decisions.

Genetic testing can alleviate fears in people who find they do not carry specific gene changes that may lead to cancer. It can also be a lifesaver. Patients who know their cancer risk can make important decisions about screening, treatment and preventive surgery, which may reduce cancer risk and cancer’s impact on one’s life. Learn more at Duke Health.

Genetic counselors, medical oncologists, gastroenterologists, gynecologists and primary care physicians work together to provide comprehensive evaluation, risk assessment and genetic testing and post-test counseling. For more information or to make an appointment, call 919.684.3181.

Clinical Cancer Genetics Cancer Genetics Duke’s hereditary cancer experts offer genetic testing and genetic counseling to people diagnosed with cancer, as well as people who may be at risk of