Are you considering CBD to help manage Hashimoto’s Disease? Here are some of the best CBD oils to help alleviate the symptoms of this condition. CBD for Hashimoto’s Disease: How Can It Help? CBD is a powerful and versatile compound; it can help regulate various functions throughout the body, including hormonal balance. With new Hashimoto's disease, also known as chronic lymphocytic thyroiditis, is an inflammation of the thyroid that causes the gland to stop producing hormones.
Compare the Best CBD Oil for Hashimoto’s Disease in 2022
Each bottle of the 750mg CBD oil tincture contains 25mg of CBD per dropper full. The oil is peppermint flavor to mask any unpleasant tastes related to CBD.
2. NuLeaf Naturals 900mg Full Spectrum Hemp CBD Oil
cbdc overall score
CBDC Evaluation Table/Score
No other flavors
Approximately 300 drops total
Natural remedy for various illnesses. NuLeaf Naturals’ CBD oil is a whole-plant extract containing a full spectrum of naturally occurring synergistic cannabinoids and terpenes.
3. Spruce 2400mg Lab Grade CBD Oil
cbdc overall score
CBDC Evaluation Table/Score
No artificial flavoring or colors
No THC-free option
Made from 100% organic and natural ingredients
The largest bottle of CBD oil that Spruce offers contains 2,400mg of CBD. This is full-spectrum CBD oil, which is the maximum possible potency. Each high potency dropper full contains 80mg of CBD. There are no flavorings in it, which allows for the most CBD to fit in the 30ml bottle.
4. Avida Full Spectrum CBD Oil Tincture 500mg
cbdc overall score
CBDC Evaluation Table/Score
Light Spearmint flavor
No other flavor
Non-THC, Non-detected in drug test
Avida Extracts Full Spectrum CBD oil is the latest iteration of the brand’s advanced Avida CORE Spectrum technology. They use a proprietary full spectrum blend, resulting in the highest naturally occurring Phyto-cannabinoids and Terpenes with THC (<0.3) to support your health.
5. cbdMD CBD Oil Tincture Natural 1500mg
cbdc overall score
CBDC Evaluation Table/Score
Various delicious flavors to choose from
cbdMD uses MCT as its carrier oil so individuals who are allergic with coconuts should consider other brand options
Has vegan, organic, and gluten-free ingredients
Free shipping for this particular product within USA
World-class customer service team
cbdMD’s CBD oil tinctures are made using only CBD sourced from medical hemp and MCT oil as a carrier oil. Tinctures are offered in orange, mint, natural, and berry flavors. Safe for daily use, the oil tinctures are packaged with a built-in rubber dropper to adjust CBD dosage easily. The packaging is made to be easy to transport and discreet to use.
6. CBDistillery THC Free CBD Oil Tinctures
cbdc overall score
CBDC Evaluation Table/Score
60-Day Satisfaction Guarantee
Dropper is a bit shaky
Oil extracted from aerial plant parts of US grown industrial hemp
Sourced from non-GMO industrial hemp grown in the USA through natural farming practices
CBDistillery’s Isolate CBD Oil Tinctures harness the power of pure CBD. CBD Isolate Oil Tinctures include 0.0% THC. When you use CBDistillery CBD Isolate Oil Tinctures, you can be assured you’re using the highest quality CBD on the market.
7. NuLeaf Naturals 300mg Full Spectrum Hemp CBD Oil
cbdc overall score
CBDC Evaluation Table/Score
No other flavors
A bit pricey compared to competitors
Approximately 100 drops total
This is one of several concentrations from NuLeaf Naturals. As the lowest concentration, it is the company’s best option for those new to CBD oil. The product is lab-tested and fully organic. It is full-spectrum, so it contains THC in small quantities.
8. cbdMD CBD Oil Tincture Natural 750mg
cbdc overall score
CBDC Evaluation Table/Score
Vegan and Gluten free
Does not ship internationally
Has a third-party lab test
Wide variety of CBD strengths and sizes
A 750mg bottle of cbdMD’s Broad Spectrum Oil Tincture does not contain THC. It also has a fairly wide flavor range which is perfect for those who prefer other taste. Vegan consumers are considered since cbdMD offers Vegan products. Aside from all of that, another reason why people love cbdMD is because it’s free from harmful chemicals.
9. Hemp Bombs 750mg CBD Oil
cbdc overall score
CBDC Evaluation Table/Score
Wide variety of flavors
Incomplete information about the product
Lab test results are complete
Does not ship to all international countries
30-day money-back guarantee
Hemp Bombs offer CBD Oil Tinctures that come in a 30ml bottle containing 750mg of CBD. They provide a wide range of flavors perfect for those that have a knack for sweets. Consumers can safely intake this because it’s free of chemicals and pesticides. Hemp Bombs also offer a 20% off on products upon subscription.
How We Rank
How CBD May Help With Hashimoto’s Disease
CBD is a nonintoxicating cannabis plant compound that may provide anti- inflammatory benefits (1) .
The phytocannabinoid (plant-based cannabinoid ) may help manage certain medical conditions (2) . It works by engaging the body’s ECS or endocannabinoid system (3) .
The ECS comprises several essential components, like the CB1 and CB2 cannabinoid receptors . These receptors help regulate many bodily functions like sleep, learning, eating, pain control, and immune and inflammatory responses (4) .
Cannabinoids are chemical substances that may help suppress inflammatory cytokine production and immune activation (5) .
Cytokines are proteins that help control the activity and growth of immune system cells, regulating the body’s inflammatory and immune responses (6) .
One study mentioned that cytokines may help induce tolerance against autoimmune thyroid diseases , including Graves disease and Hashimoto’s thyroiditis (7) .
Graves disease is an autoimmunity disorder caused by excessive thyroid production leading to hyperthyroidism (8) .
Symptoms of hyperthyroidism include rapid heartbeat, weight loss , muscle weakness , and frequent bowel movements (9) .
Benefits and Uses of CBD for Hashimoto’s Disease
There has been no conclusive clinical evidence indicating CBD directly helps with Hashimoto’s disease . Additional research is required to determine CBD’s potential in managing this autoimmune condition and other thyroid disorders .
Hashimoto’s thyroiditis causes the thyroid to become inflamed or enlarged (10) . One primary benefit of CBD is as an anti- inflammatory agent (11) . This may be one area of interest for research on the role of CBD in addressing Hashimoto’s disease .
Another symptom of Hashimoto’s disease is joint pain (12) . Animal studies suggest CBD may have pain-relieving properties (13) .
However, the results of animal studies still need to be validated in human studies.
CBD Dosage for Hashimoto’s Disease
There are currently no standard CBD dosage guides specific to Hashimoto’s disease . However, the general recommendation is to start with a lower dose when taking CBD (14) .
Factors that may affect CBD dosage include diet, exercise, genetics, stress levels, and existing health conditions (15) .
If you have symptoms of Hashimoto’s disease or other medical conditions, consult your doctor for proper diagnosis and treatment before taking CBD or deciding on a specific CBD dosage.
How to Take CBD Oil for Hashimoto’s Disease
There are various delivery methods to take CBD oil to help manage the symptoms of Hashimoto’s disease and other thyroid conditions . These methods are the following:
- Sublingual administration : CBD oil is delivered sublingually or under the tongue, allowing CBD to bypass the digestive tract and enter the bloodstream directly.
Sublingual methods include CBD oil tinctures using droppers or oromucosal sprays.
- Oral administration : CBD oil passes through the digestive tract before entering the bloodstream.
Some oral CBD products include capsules and edibles , such as CBD gummies and chews.
- Topicalapplication : CBD oil is applied directly to the skin. Topical products include creams , lotions, balms, and ointments.
- Vaping : CBD is delivered into the body through inhalation. Vaping is considered one of the fastest ways to administer CBD into the body (16) .
However, vaping can cause potential health risks related to lung disease (17) . Consult your doctor before using vape products if you have existing health conditions.
How Long Does CBD Take to Help With Hashimoto’s Disease ?
There are no specific studies to date that focus on onset times of CBD for Hashimoto’s disease .
Generally, the onset time for CBD oral ingestion is around 30 to 90 minutes. Meanwhile, CBD may take effect 15 to 30 minutes after application using sublingual and topical methods . For CBD inhalation, the onset time is about 2 to 15 minutes (18) .
How Long Will CBD Help With Hashimoto’s Disease ?
To date, conclusive scientific data is insufficient to determine the duration of CBD’s effects on Hashimoto’s disease .
A 2018 review stated that CBD administered at 5 milligrams (mg) and 20mg doses using oromucosal sprays has a half-life of 1.4 and 10.9 hours (19) .
Half-life is the period a drug takes to decrease its concentration or quantity within the body by 50%.
Side Effects and Risks of Using CBD for Hashimoto’s Disease
At present, no specific studies determining CBD’s side effects on individuals with Hashimoto’s disease have been conducted.
In general, CBD’s side effects include diarrhea, fatigue, appetite loss, drowsiness, and dry mouth (20) .
Choosing the Right CBD for Hashimoto’s Disease
To choose the right CBD product to help manage the symptoms of Hashimoto’s disease and maintain thyroid function , you must consider various factors, such as extraction methods or types of CBD products .
Manufacturers extract CBD from the cannabis plant using extraction methods such as carbon dioxide (CO 2 ), hydrocarbon, or ethanol. Afterward, CBD is categorized as full-spectrum , broad-spectrum, or isolate.
Full-spectrum CBD oil contains all the cannabis plant compounds and cannabinoids , such as tetrahydrocannabinol ( THC ), flavonoids, and terpenes.
Flavonoids give plants their distinct colors, while terpenes produce an aromatic effect in plants (21) .
Broad-spectrum CBD oil also contains most compounds in full-spectrum CBD oil . However, broad-spectrum CBD products do not contain THC .
Meanwhile, isolates contain pure CBD only. No other cannabinoids or compounds are included.
You may consider isolates or broad-spectrum products if you prefer to take CBD oil without THC ’s psychoactive effects.
Legality of CBD
The 2018 Farm Bill removed hemp-based CBD products with less than 0.3% THC from the list of controlled substances.
Still, CBD products with more than 0.3% THC are illegal under federal law (22) .
Check your state’s laws and review your CBD product ’s THC content to determine whether CBD is legal in your area.
What Is Hashimoto’s Disease ?
Hashimoto’s disease , sometimes called chronic lymphocytic thyroiditis , is an autoimmune disease that affects the thyroid gland . The thyroid gland produces thyroid hormones needed for metabolism.
The disease causes immune cells to attack thyroid hormone -producing cells, resulting in hypothyroidism or thyroid hormone production decline.
The progression of Hashimoto’s disease may lead to goiter or thyroid gland enlargement.
Symptoms of Hashimoto’s disease include (23) :
- Weight gain
- Muscle pain
- Hair loss
- Dry skin
- Slow heart rate
Other signs of Hashimoto’s disease are muscle weakness , joint pain , increased sleepiness, and irregular menstrual bleeding (24) .
Doctors diagnose Hashimoto’s disease using blood tests , thyroid-stimulating hormone ( TSH ) tests, or thyroid antibody tests.
If Hashimoto’s disease progresses to hypothyroidism , doctors may prescribe thyroid medications like levothyroxine ( Synthroid , Levoxyl, Levothroid) (25) .
Your doctor may recommend radioactive iodine in the case of hyperthyroidism .
How can CBD help with Hashimoto’s disease?
CBD is a cannabinoid known to provide anti- inflammatory benefits (26) . Cannabinoids may help suppress immune activation and inflammatory cytokine production (27) .
Cytokines play a role in managing autoimmune thyroid diseases , including Hashimoto’s thyroiditis (28) .
What evidence or research exists to say that CBD oil helps with Hashimoto’s disease?
Joint pain is one symptom of Hashimoto’s disease (29) . Animal studies show CBD may help reduce pain (30) . However, more studies are needed to validate the pain-relieving benefits on humans.
Is there any evidence that CBD can make Hashimoto’s disease worse?
There is presently no direct evidence suggesting CBD worsens Hashimoto’s disease .
Will CBD interact with any current medication I may be taking for Hashimoto’s disease?
CBD may prevent the activity of cytochrome P450 enzymes that metabolize various pharmaceutical drugs. Inhibiting these enzymes may cause the drugs to take longer to take effect (31) .
Are there other treatments I should consider alongside CBD to help with Hashimoto’s disease?
Exercising, eating a balanced diet, and sleeping well can help manage the symptoms of Hashimoto’s disease and maintain thyroid health .
Ask your doctor for more information about other remedies, nutrients , supplements , or alternative meds you may take with CBD.
Can I fail a drug test if I use CBD for Hashimoto’s disease?
CBD products with less than 0.3% THC do not cause a drug test failure. However, frequent and prolonged CBD oil use may cause THC levels in your body to increase (32) , increasing the probability of a positive result.
What is the dosage for Hashimoto’s disease?
To date, there are no standard CBD dosage guides for Hashimoto’s disease . In general, users may start taking CBD at a lower dose (33) .
What are the possible side effects of CBD for Hashimoto’s disease?
CBD’s known side effects include drowsiness, appetite loss, dry mouth, fatigue, and diarrhea (34) .
CBD for Hashimoto’s Disease: How Can It Help?
CBD is a powerful and versatile compound; it can help regulate various functions throughout the body, including hormonal balance.
With new research emerging every month, scientists are discovering new health benefits of CBD — but can it be used to treat Hashimoto’s disease and other thyroid conditions?
Most benefits of CBD stem from its modulatory actions on the immune system. Cannabinoid receptors are also found on the surface of hormonal glands, including the thyroid.
If you have Hashimoto’s thyroiditis (or any other autoimmune disease), it means your body is losing the war against an aggressive immune system.
Although there are no direct studies focusing on using CBD for Hashimoto’s, several research papers suggest that it can improve the quality of life of patients with thyroid disorders.
Today, we elaborate on how you can use CBD oil for Hashimoto’s to control its symptoms and regulate your immune system.
What Is Hashimoto’s Disease?
Hashimoto’s disease, also known as chronic lymphocytic thyroiditis, is an autoimmune disease of the thyroid gland. It causes a person’s immune system to become aggressive toward the thyroid (autoimmunity), damaging to the point where it can’t produce its own hormones any longer.
Hashimoto’s involves inflammation of the thyroid gland and is the major contributor to hypothyroidism — a condition characterized by an underactive thyroid.
Some patients with Hashimoto’s can develop a goiter, which is a lump on the thyroid triggered by inflammation and causing neck discomfort. One way to diagnose Hashimoto’s is through blood test results that check thyroid-stimulating hormone (TSH) and thyroid hormones (FT4 and T4).
Symptoms of Hashimoto’s Disease
Hashimoto’s disease develops more often in women. However, it can occur at any age and even men and children can suffer from it.
The most common symptoms of Hashimoto’s disease include:
- Weight gain
- Dry skin
- Puffy face
- Ple skin
- Hair loss
- Sensitivity to cold
The symptoms may not be noticeable at first, but as the disease progresses over the years, their severity will increase — deteriorating your quality of life.
Conventional Treatments for Hashimoto’s (High Risk)
Researchers have yet to find the underlying cause of Hashimoto’s disease and other thyroid disorders. However, the main hypothesis revolves around chronic inflammation caused by an aggressive immune system.
The conventional Hashimoto treatment involves taking levothyroxine, which is a thyroid medication using a specific hormone to level the deficiency in thyroid hormones.
Unfortunately, when you’re prescribed levothyroxine, you usually need to take it for life.
Taking high doses of the drug can have negative side effects, such as osteoporosis or irregular heartbeats (arrhythmia). Your doctor should titrate the medicine appropriately, but most of the time, the dose is gradually increased to the point where another treatment must be considered.
Meanwhile, CBD may offer a theoretically safer way to treat people with Hashimoto’s.
Can CBD Oil Help Treat Hashimoto’s?
CBD is one of over 115 cannabinoids identified in cannabis plants. Unlike the other major cannabinoid, THC, CBD doesn’t cause mind-altering effects when you take it. Researchers have found that cannabinoids, including CBD, offer remarkable anti-inflammatory properties.
A 2010 review of studies published in the journal Future Medicinal Chemistry found that daily supplementation with CBD inhibited disease progression in mice.
The research team learned that CBD decreased the amount of pro-inflammatory cytokines, which are known to trigger inflammatory reactions.
Cytokines have been highlighted as one of the contributors to the onset of thyroid diseases, such as Hashimoto’s.
In a 2011 study, the authors concluded that cytokines play an important role in the pathogenesis (formation) of autoimmune disorders in the thyroid. They also found that cytokine modulation may help treat autoimmune conditions.
A 2020 study mentioned CBD and other cannabinoids as potential immunosuppressants due to their ability to block the production of inflammatory cytokines. These properties suggest that CBD — and cannabis in general — may have the potential to curb chronic inflammation in the body.
Another study showed that CBD is involved in regulating inflammatory response and expression by acting on various receptors throughout the body. The authors noted that CBD administration in animals could inhibit the release of excess cytokines.
Since CBD can reduce the number of substances that trigger inflammation, it may theoretically be used as an adjunctive treatment for Hashimoto’s — at least for symptom control.
However, there are no direct studies that would examine CBD’s impact on thyroid disorders, including Hashimoto’s disease. No clinical trials exist to prove the long-term efficacy of CBD for Hashimoto’s as a monotherapy.
How does CBD Work to Help with Hashimoto’s?
In a study published in 2017, the research team mentions that specific receptors in the human body could modulate the production of cytokines. The CB1 and CB2 receptors, which are the components of the endocannabinoid system (ECS), are said to play a part in signaling that influences cytokines.
The ECS promotes and helps to maintain homeostasis throughout the body. It regulates various physiological functions, including inflammation.
CBD influences the ECS structures, particularly the CB2 receptor — which would explain its anti-inflammatory effects.
On top of acting on CB1 and CB2 receptors, CBD may also use other pathways that reduce inflammation.
Meanwhile, the authors of a 2015 study that evaluated the ECS’s role in thyroid tumors found that cannabinoid receptors are linked to tumor malignancy.
They concluded that CB1 and CB2 receptors are potential therapeutic targets for future treatments.
Another study also found that CB1 receptors of the ECS control hormone production in the thyroid.
Thyroid hormones help regulate body temperature, energy, and other important metabolic functions.
Since CBD is the modulator of the ECS, there’s a chance that it can be used to regulate thyroid conditions by acting on its structures.
However, more clinical human studies are needed to confirm CBD’s long-term efficacy in treating Hashimoto’s.
5 Reasons to Consider Taking CBD for Hashimoto’s
Looking at the above studies, this may be enough to convince you to try CBD for Hashimoto’s. That being said, there’s more to CBD and thyroid than just symptom control.
After all, conventional treatments are also focused on managing the symptoms of thyroid disorders.
Here’s why you may want to consider taking CBD for Hashimoto’s.
1. Safety Profile
If therapy is effective, that doesn’t mean it’s safe in the long run.
There are plenty of treatments in contemporary medicine which have been shown to be effective — but cause negative side effects.
On the other hand, there are plenty of therapies with the potential to treat Hashimoto’s while being very safe for our health.
The degree of a medication’s safety is referred to as its safety profile.
CBD has an excellent safety profile. Even doses as high as 1,500 mg administered daily for several weeks didn’t cause any dangerous side effects in patients.
The side effects of CBD are benign and include changes in appetite, dry mouth, dizziness, and — in case you took way too much — diarrhea.
Any healthy foods can get you these kinds of side effects if you take them in excess amounts.
According to the WHO, CBD is safe and well-tolerated in humans.
That being said, CBD can interact with many pharmaceutical medications. It can compromise the liver’s ability to metabolize these drugs, resulting in either too low or too high concentrations of the drug in the bloodstream.
If you’re unsure if you can take CBD for Hashimoto’s alongside your thyroid medications, consult a holistic doctor experienced in cannabis use.
2. Additional Benefits Aside from Hashimoto’s
Another reason to consider using CBD oil for Hashimoto’s is its versatility.
Medications are made to impact specific enzymes or receptors and may not interact with any other cellular components.
Unlike medications, herbal extracts like CBD oil can act on several different molecular pathways. CBD has over 65 such targets. It greatly helps one’s health due to its various benefits.
Additional benefits may include:
- Reduced anxiety thanks to the modulation of GABA, serotonin, and anandamide (Hashimoto’s patients often experience anxiety)
- Improved sleep as a result of the circadian rhythm regulation (many thyroid patients suffer from insomnia)
- Reduced pain due to its analgesic properties (people with Hashimoto’s often have chronic pain)
- Reduced inflammation (inflammation impacts conversion from T4 to T3)
If you have any of these symptoms, you could use CBD oil to improve your overall quality of life with Hashimoto’s.
3. Complementary Effects with Other Treatments
The current treatment paradigm for Hashimoto’s has caused many patients to look for natural alternative therapies because it’s just a standard “wait and see approach.”
As a patient, you don’t want to rely on taking synthetic hormones for life.
The good news is that you can use CBD along with other lifestyle modifications to achieve a better result. When you see the big picture, you’ll notice that Hashimoto’s requires a multifaceted approach, not just some miracle pill.
Changing your diet, reducing your stress, and supplementing CBD oil can help your body get back on track and heal itself from excess inflammation — but they don’t guarantee that you’ll be able to reverse your condition.
They are, however, much safer than conventional methods. Taking CBD oil on a daily basis can help improve the functioning of your ECS — translating into more effective management of vital functions throughout the body.
This, on top of an anti-inflammatory diet, proper stress hygiene, and an active lifestyle, can help you achieve better results for your thyroid health overall.
CBD oil is legal in all 50 states and you can buy it without a prescription — unlike thyroid medications, which must be prescribed by a doctor.
In most cases, patients may know more about their disease and possible treatments than their doctor and yet they’re not able to get the right medication.
Because they are limited by the doctor and the prescription.
If your doctor isn’t willing to prescribe you the medication you’re asking for, your knowledge doesn’t matter.
This problem is nonexistent with CBD and other herbal supplements.
Nevertheless, we still advise you to consult a doctor before adding CBD oil to your daily routine. Doing so will help you find the right dosage to start with — not to mention that you can avoid negative interactions with other medications.
5. Patient Success Stories
Clinical trials are important for evaluating the long-term efficacy and safety of certain medications, but all clinical trials start with anecdotal evidence, better known as success stories of patients.
Both types of evidence have strong value. While clinical studies are very helpful, they don’t always tell the full story. The results can be interpreted in any way that suits the thesis of the study’s author.
Moreover, some clinical trials aren’t published, so we don’t always get to see their results. The author simply doesn’t have to publish the study if it doesn’t show the results they were looking for.
Some studies can be run 3-4 times until they finally yield satisfying results.
Last but not least, just because studies show that something is effective doesn’t mean it will work for every individual.
Doctors are often excited about novel therapies when they read about them in scientific magazines only to find out that they’re not nearly as effective as they believe them to be in the real world.
When it comes to patient success stories, they take a different approach.
There are no controls that clinical studies can provide but they still provide value as a “proof of concept.”
Are there any direct studies on the effectiveness of CBD for Hashimoto’s?
Do we see positive stories of patients who have taken it and seen great results?
The so-called anecdotal evidence often provides inspiration for clinical trials.
How to Choose CBD Oil for Hashimoto’s
CBD can be found in three major types: full-spectrum, broad-spectrum, and CBD isolate.
The full-spectrum type of CBD is the most popular because it contains cannabinoids, flavonoids, terpenes, and trace amounts of THC. Together, these compounds create the entourage effect, which means that the plant-based compounds work together in synergy — producing greater therapeutic effects than each of them alone.
Broad-spectrum CBD is another popular type. This option contains the same compounds as full-spectrum CBD — except for the THC content.
The third variant is CBD isolate. This is just pure CBD in crystalline or powdered form. It carries the highest dose of CBD per serving; it’s also odorless and flavorless, which is why some people prefer it over the two above formats. That being said, CBD isolates lack the entourage effect, so they are less desired among consumers.
Tips for Buying CBD Oil for Hashimoto’s
- Look for a certificate of analysis (COA) for the chosen product. This document shows that the product has undergone proper testing and its contents match the ones that are listed on the label.
- Read product reviews and do a solid background check on your potential vendor. If buying from a local store, make sure to check if it has the proper authorization to sell CBD extracts.
- The best CBD oils for Hashimoto’s are made from organic hemp; it’s the most dependable source of high-quality CBD.
- Ensure that there are no limits to the availability of CBD in your state. Hemp-derived CBD is federally legal but the state laws are dynamic, so it’s always worth it to keep yourself up to date with your local regulations surrounding cannabis.
- Consult a holistic doctor, preferably someone experienced in cannabis use, before buying CBD products.
CBD Dosage for Hashimoto’s
Since CBD isn’t regulated by the FDA, there are no official dosage guidelines when it comes to using CBD for Hashimoto’s, or any other condition for that matter.
There are a few factors you should consider when determining your dose of CBD, including:
- Tolerance to CBD
- Severity of symptoms
- Expected results
The best approach to starting your CBD regime is to take a small amount of CBD (5 or 10 mg) and gradually increase it until you come to the point where you experience the desired results without any side effects.
You can also use different studies on CBD for specific symptoms to analyze different dosages try them out on yourself.
How to Take CBD for Hashimoto’s
CBD is available in many different forms, including CBD oils, edibles, capsules, vapes, and topicals.
Beginners often choose edibles or capsules because they contain a fixed dose of CBD per serving. Since oral forms of CBD need to pass through the digestive system, they have a delayed onset (up to 90 minutes) but last longer than other forms (up to 10 hours).
More experienced users turn to CBD oil because it combines dosage accuracy with a higher bioavailability and faster onset. CBD oils absorb through the mucous membrane in your mouth, avoiding the first-pass metabolism in the liver. As a result, your body receives more active ingredients. The CBD also acts faster (15-30 minutes) lasting for up to 6 hours.
Vaporization offers the fastest and most effective way to consume CBD. When you inhale CBD through a vape pen, it travels to your bloodstream through lung tissues — producing almost instantaneous effects. Vapes have the highest bioavailability (56%) and they last for up to 4 hours.
For localized problems, such as inflammatory flare-ups, you can use CBD topicals such as creams, balms, lotions, or gels. They target the CB2 receptors in your skin, providing relief from inflammation and pain. The absorption rate and duration of topicals vary between different formulations.
CBD vs Other Natural Remedies for Hashimoto’s
Diet modifications are one of the first steps that a person with Hashimoto’s should take. This includes choosing animal foods rich in zinc, as well as fruits and vegetables.
Vegetables contain phytosterols, which are anti-inflammatory compounds. Low-calorie fruits have high levels of antioxidants and can help the body recover from the damage caused by inflammation.
Animal-based foods high in zinc, such as meats and eggs, are recommended several times a week. Zinc deficiency is often cited as one of the causes of hypothyroid conditions.
Iodine supplements are another possible option, but they need to be taken in the right form, as certain forms of iodine can be toxic for the body and actually exacerbate your condition.
Other Types of Thyroid Disorders
Aside from Hashimoto’s disease, people can suffer from one of the following thyroid conditions that are triggered by the chronic inflammation of this gland:
Hyperthyroidism occurs where the gland produces more hormones than the body actually needs. Excessive thyroid hormone production can result in symptoms such as irritability, fast heart rate, weight loss, muscle weakness, and nervousness.
Grave’s Disease is another thyroid disorder that occurs when a person’s immune system attacks the thyroid gland by accident. This leads to the production of excess thyroid antibodies.
People with Grave’s disease often have high blood pressure and increased metabolism as a result of enlarged thyroid glands.
Key Takeaways on Using CBD for Hashimoto’s
CBD has been shown to reduce inflammation and pain, showing as a potential therapeutic agent in the treatment of Hashimoto’s disease.
There is some evidence to support the use of CBD in reducing chronic inflammation associated with thyroid conditions. Several studies have shown that CBD may block the excess activation of the immune system by inhibiting the release of pro-inflammatory proteins.
Researchers believe that the endocannabinoid system (ECS) is involved in regulating the activity of hormonal glands — including the thyroid. By modulating cannabinoid receptors, CBD can act as an adaptogen — adjusting the production of thyroid hormones.
More clinical trials are needed to confirm CBD’s efficacy for Hashimoto in the long run, but current findings are very promising, to say the least.
You can also use CBD oil to help with other symptoms associated with Hashimoto’s, including anxiety, pain, sleep problems, and low energy levels.
Always consult a doctor before buying a CBD product for any condition. Doing so will help you figure out the best CBD dosage for your situation and avoid potential CBD-drug interactions.
Do you take CBD for Hashimoto’s? Let us know by leaving a comment below!
- Nagarkatti, P., Pandey, R., Rieder, S. A., Hegde, V. L., & Nagarkatti, M. (2009). Cannabinoids as novel anti-inflammatory drugs. Future medicinal chemistry, 1(7), 1333–1349. (1)
- Ganesh, B. B., Bhattacharya, P., Gopisetty, A., & Prabhakar, B. S. (2011). Role of cytokines in the pathogenesis and suppression of thyroid autoimmunity. Journal of interferon & cytokine research: the official journal of the International Society for Interferon and Cytokine Research, 31(10), 721–731. (2)
- Khodadadi, H., Salles, É. L., Jarrahi, A., Chibane, F., Costigliola, V., Yu, J. C., Vaibhav, K., Hess, D. C., Dhandapani, K. M., & Baban, B. (2020). Cannabidiol Modulates Cytokine Storm in Acute Respiratory Distress Syndrome Induced by Simulated Viral Infection Using Synthetic RNA. Cannabis and cannabinoid research, 5(3), 197–201. (3)
- Atalay, S., Jarocka-Karpowicz, I., & Skrzydlewska, E. (2019). Antioxidative and Anti-Inflammatory Properties of Cannabidiol. Antioxidants (Basel, Switzerland), 9(1), 21.
- Fitzgerald, J. C., Weiss, S. L., Maude, S. L., Barrett, D. M., Lacey, S. F., Melenhorst, J. J., Shaw, P., Berg, R. A., June, C. H., Porter, D. L., Frey, N. V., Grupp, S. A., & Teachey, D. T. (2017). Cytokine Release Syndrome After Chimeric Antigen Receptor T Cell Therapy for Acute Lymphoblastic Leukemia. Critical care medicine, 45(2), e124–e131.
- Lakiotaki, E., Giaginis, C., Tolia, M., Alexandrou, P., Delladetsima, I., Giannopoulou, I., Kyrgias, G., Patsouris, E., & Theocharis, S. (2015). Clinical Significance of Cannabinoid Receptors CB1 and CB2 Expression in Human Malignant and Benign Thyroid Lesions. BioMed research international, 2015, 839403. (6)
- Hillard C. J. (2015). Endocannabinoids and the Endocrine System in Health and Disease. Handbook of experimental pharmacology, 231, 317–339. https://doi.org/10.1007/978-3-319-20825-1_11 (7)
Nina created CFAH.org following the birth of her second child. She was a science and math teacher for 6 years prior to becoming a parent — teaching in schools in White Plains, New York and later in Paterson, New Jersey.
CBD Oil for Hashimoto’s Disease – September 2022
Why People Are Turning to CBD for Hashimoto’s Disease
Hashimoto’s disease , also called chronic lymphocytic thyroiditis , is an autoimmune condition where the thyroid gland fails to function correctly (7) . The disorder causes a person’s immune system to attack the thyroid ( autoimmunity ), damaging it to the point where it stops producing hormones.
The disease involves inflammation of the thyroid gland and is the most common cause of hypothyroidism ( underactive thyroid ) in the United States (8) .
In some cases of Hashimoto’s disease , the inflammation can cause the thyroid gland to be enlarged ( goiter ), causing neck discomfort. One way to diagnose the disease is through blood test results that measure thyroid-stimulating hormone ( TSH ) and thyroid hormones (FT4 and T4).
Hashimoto’s disease occurs more often in women. However, it is seen at any age and may develop in men and children (9) .
The most common signs of Hashimoto’s disease include fatigue, constipation, joint pain , pale skin, puffy face, weight gain , dry skin , hair loss , and increased sensitivity to cold.
A person with the condition may not notice its symptoms at first, as the disease typically progresses slowly over the years (10) .
Researchers are unsure of what causes some individuals to develop thyroid problems , like Hashimoto’s disease .
The conventional treatment for Hashimoto’s disease is a dose of levothyroxine ( Synthroid ) (11) . This thyroid medication is a manufactured form of a specific hormone used to treat the deficiency caused by the condition – and is usually prescribed for life.
Taking an excessive amount of the drug can lead to harmful effects, such as irregular heartbeats and osteoporosis. However, you and your doctor will titrate the medicine appropriately. You should not stop taking it or adjust this medicine without talking to your doctor first.
Meanwhile, cannabidiol ( CBD ) may theoretically offer a supplementary solution to treating people with Hashimoto’s disease .
CBD is one of many compounds obtained from cannabis plants that do not cause mind-altering effects upon consumption. Researchers believe that cannabinoids, like CBD , have anti-inflammatory properties.
A 2010 review published by the journal Future Medicinal Chemistry found that daily cannabidiol intake inhibited disease progression in mice (12) .
The authors learned that the CBD -treated subjects showed decreased pro-inflammatory cytokines or molecules that cause inflammatory reactions.
Cytokines have been implicated in the development of thyroid diseases , such as Hashimoto’s thyroiditis .
Authors of a 2011 study learned that cytokines play an essential role in the pathogenesis of autoimmune disorders of the thyroid. They also discovered that modulating cytokine responses may help treat autoimmune diseases (13) .
A study in 2020 mentioned that cannabinoids, like CBD , may suppress immune activation and production of inflammatory cytokines. This action suggests that the cannabis compound may have the potential to reduce excessive inflammation in the body (14) .
Another study revealed that cannabidiol is involved in controlling inflammatory response and expression through various bodily receptors. The authors of the study reported that CBD administration in an animal model could inhibit cytokine response (15) .
CBD has been shown to reduce substances that cause inflammation. It may theoretically be used as a therapeutic agent to alleviate the symptoms of thyroid disorders , like Hashimoto’s disease .
However, studies on cannabidiol and thyroid health conditions are yet non-existent. No clinical trials exist to prove that CBD can effectively treat the symptoms of Hashimoto’s disease and other thyroid issues .
How CBD Oil May Work to Help with Hashimoto’s Disease
A study published in 2017 mentioned that specific receptors in the human body could affect cytokine production (16) . The CB1 and CB2 receptors, which are primarily used by the endocannabinoid system (ECS), are said to modulate signaling that influences cytokines.
The ECS regulates various bodily functions, one of which is inflammation (17) . Researchers learned that CB1 and CB2 cannabinoid receptors are involved in managing inflammation-causing cytokines (18) .
Cannabidiol reportedly binds to these ECS structures, particularly with the CB2 receptor, which may explain its anti-inflammatory properties (19) .
Besides CB1 and CB2 receptor activation, the compound may also have other actions that may reduce inflammation.
Meanwhile, researchers of a 2015 study analyzed the endocannabinoid system ‘s role in thyroid tumors and found that its receptors are associated with tumor malignancy (20) .
They learned that CB1 and CB2 receptors influenced thyroid tumors and hypothesized that both could be targets for future therapies.
Another study also implicated the CB1 receptors of the ECS in the control of thyroid hormone output (21) .
Thyroid hormones help regulate body temperature, among many other important metabolic functions, by increasing the available energy in the body.
Since CBD is said to stimulate both CB1 and CB2 receptors, there is a possibility that the compound may be used to influence thyroid conditions through this action.
However, more clinical data on human subjects is needed to confirm CBD ‘s efficacy for thyroid disorders .
The Pros and Cons of CBD Oil for Hashimoto’s Disease
- Using CBD may theoretically help people with Hashimoto’s disease . Studies revealed that CBD might have anti-inflammatory properties, which the compound expresses through its interaction with receptors in the body.
- Unlike THC ( tetrahydrocannabinol ), the psychoactive compound of cannabis, CBD does not cause mind-altering effects upon consumption.
- Individuals can purchase and use CBD in most areas in the United States. In places where CBD is sold legally, users can buy CBD products even if they do not have a prescription from a doctor.
- The U.S. Food and Drug Administration (FDA) recognizes the potential health benefits of cannabis constituents, such as CBD (22) .
- The World Health Organization (WHO) claims that CBD is well-tolerated in humans, according to several controlled and open-label trials (23) . Subjects were reported to have not developed substance dependence with the use of CBD .
- There is a significant lack of human studies on CBD ‘s efficacy for Hashimoto’s disease , making it difficult to determine its effectiveness, if any, in treating the condition.
- Epidiolex, a drug used to treat two rare forms of epilepsy, is the only CBD product approved by the FDA. The agency has not yet allowed any other CBD marketing application for the treatment of a specific disease or condition (24) .
- A review in 2017 assessed the safety and possible side effects of CBD use. Although it has a favorable safety profile, CBD can still cause interactions with other prescription medications that can lead to adverse reactions (25) .
- Many CBD products , particularly items sold online and in some physical dispensaries, are prone to mislabeling (26) . Users who buy CBD from these channels are at risk of consuming more or less of the compound than expected.
How CBD Oil Compares to Alternative Treatments for Hashimoto’s Disease
Multi-disciplinary diets may help improve the quality of life and thyroid function of patients with Hashimoto’s thyroiditis (27) .
According to a study that evaluated the various diets for the condition, consuming vegetables, fruits, and animal foods rich in zinc are recommended by experts (28) .
Eating vegetables several times a day is advised because they contain phytosterols, which are compounds present in plants that have shown anti-inflammatory activity.
However, raw cruciferous vegetables, like cabbage, should only be eaten once a week as these can interfere with thyroid hormone production .
The consumption of fruits at least once a day is also suggested as these are abundant in polyphenols, which have anti-inflammatory and antioxidant properties (29) .
Eating animal-based foods that are high in zinc, such as meats and eggs, are recommended several times a week. According to a report, zinc deficiency could be linked to hypothyroid (30) .
Meanwhile, iodine supplements are not advised for patients with Hashimoto’s disease . People with abnormal thyroid glands risk exacerbating their condition if they take too much iodine (31) .
Cannabidiol is believed to have anti-inflammatory properties that could contribute to alleviating thyroid disorder symptoms. CBD products are often promoted as an alternative to combat inflammation.
Meanwhile, CBD capsules containing zinc are sold by some brands. These CBD products are often advertised as useful in maintaining a healthy lifestyle.
How to Choose the Right CBD for Hashimoto’s Disease
There are currently three types of CBD sold today: full-spectrum, broad-spectrum, and CBD isolates.
The most popular of the three is the full-spectrum CBD . This variant contains all of the phytocannabinoids present in Cannabis sativa plants.
CBD oil labeled as full-spectrum has flavonoids, terpenes, THC , and other minerals. The ideal full-spectrum CBD oil has high amounts of cannabidiol while containing small amounts of other compounds.
Broad-spectrum CBD is the next type of cannabidiol product. This variant has the same compounds as that of full-spectrum except for the THC content.
Since THC is psychoactive and often associated with medical marijuana , some individuals prefer to buy broad-spectrum CBD because it does not have the psychoactive compound.
The third variety of CBD is called isolates. CBD isolates are usually sold in crystalline or powdered form.
People looking to purchase pure CBD often decide to get CBD isolates. CBD products containing only pure cannabidiol do not have a distinct smell or taste.
Whichever type of CBD a person chooses, it is vital to select the best quality product available to maximize its health benefits.
Follow these tips to choose only the best CBD oil for Hashimoto’s disease :
- Get a certificate of analysis (COA) or the laboratory report of the CBD product chosen. This document is essential since it indicates that the product has undergone proper testing and contains exactly the specifications mentioned on the label.
- Read product and shop reviews if purchasing from an online CBD store. If deciding to buy from a physical dispensary, check if the establishment has the proper authorization to sell cannabidiol products.
- Buy organic CBD obtained from hemp plants. Industrial hemp is the most dependable source for high-quality cannabidiol .
- Ensure that the legalities involving CBD are followed in the state where one plans to buy and use it.
- Talk to a health care expert, preferably someone experienced in using medical cannabis, before buying any CBD product .
CBD Dosage for Hashimoto’s Disease
The FDA has not approved a CBD product for treating patients with Hashimoto’s disease . Therefore, no official guidelines are available on the proper dosage of CBD for the condition.
However, some users believe that a few factors need to be considered in determining the right dose of CBD .
A person’s body weight and the amount of CBD content in each product are two of the most commonly cited factors.
How to Take CBD Oil for Hashimoto’s Disease
Taking CBD oil in the form of edibles or capsules is the most straightforward way of consuming CBD . For beginners, CBD gummies , brownies, and tablets are recommended.
CBD tinctures that allow users to apply CBD oil under the tongue is suitable for those who want to control the amount of CBD they take.
Meanwhile, CBD , in the form of topicals, like balms, creams, and salves, may be used in massage therapies for relaxation and well-being .
Other Types of Thyroid Disorders
The following are the other common disorders associated with inflammation of the thyroid.
People with hyperthyroidism experience an overactive thyroid wherein the gland produces hormones in excess.
Grave’s disease is a common cause of this disorder. Excessive thyroid hormone levels can lead to symptoms, such as nervousness, irritability, fast heart rate , muscle weakness , and weight loss .
Grave’s disease is another endocrine system disorder that happens when the body’s immune system attacks the thyroid gland by mistake. As a result, a body part produces excess thyroid antibodies .
Patients with Grave’s disease often have enlarged thyroid glands , high blood pressure , and increased metabolism.
CBD has yet to be shown as a potential therapeutic agent in reducing inflammation prevalent in Hashimoto’s disease . There is some evidence, however, related to CBD and general inflammation which may or may not apply to the auto-immune process involved in Hashimoto’s disease.
Several studies have revealed that cannabidiol might suppress immune activation and the production of pro-inflammatory molecules.
Researchers believe that CBD activates certain cannabinoid receptors in the body to exert its anti-inflammatory effects. The CB2 receptor of the endocannabinoid system was especially mentioned.
Although CBD is said to have a favorable safety profile, there is a significant lack of clinical trials on CBD and its efficacy in treating Hashimoto’s thyroiditis .
Users should consult a doctor, particularly one who is experienced in cannabis products, before purchasing any CBD product for their condition.