CBD Oil And Viagra Interaction

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Can you mix CBD and Viagra together? Despite the need for more research, it seems generally safe to combine CBD with Viagra. Cannabidiol or CBD may prolong the effects of sildenafil (Viagra) — but is this combination safe? What are the risks?

Can You Use CBD And Viagra Together

Despite the need for more research, it seems generally safe to combine CBD with Viagra.

Can you mix CBD and Viagra Together? For those that use CBD products and the blue pill known as Viagra, it’s helpful to know the answer to this question

Marijuana and marijuana-derived products are becoming more and more popular all over the world, but few people know what CBD or viagra are or how they work. CBD (Cannabidiol) is the non-psychoactive compound found in cannabis, which you may already know by its other name, hemp.

It’s been used for centuries to treat various ailments, but it only became available in the U.S. without a prescription in 2018 after many years of research on the plant and its effects on patients with certain conditions, particularly chronic pain patients.

What Is Viagra?

Viagra is a medication that contains the active ingredient sildenafil. It’s used to treat erectile dysfunction (ED) in men. ED is when you can’t get or keep an erection. Viagra relaxes muscles and increases blood flow to particular areas of the body, which helps you get and maintain an erection. Men who have ED take viagra as needed before sexual activity.

Viagra has been prescribed for more than 20 years and is the most popular treatment for ED. It’s also available as a generic medication.

Viagra is manufactured by Pfizer Inc., was approved to market in the U.S. in March 1998, and became available on March 27, 1998.

What Is CBD?

Cannabidiol (CBD) is one of over 60+ cannabinoids found in cannabis plants. Unlike tetrahydrocannabinol (THC), it does not produce any psychoactive effects or feelings of being high. The FDA also recognizes CBD as a safe and effective medical treatment for children with epilepsy, anxiety, PTSD, autism, seizures, and diabetes. It can also be used to relieve joint pain and promote general health.

Along with THC, CBD produces the chemical compound called cannabigerol (CBG). CBG has been found to help regulate the human immune system’s reaction to viral infections such as influenza. It may also be effective against antibiotic-resistant bacteria that cause serious illnesses like MRSA infections and drug-resistant tuberculosis.

The University of Colorado Boulder suggests that CBD has anti-inflammatory properties that can help reduce inflammation associated with Crohn’s disease as well as other autoimmune diseases like psoriasis and arthritis.

In some experimental models, CBD benefits include acting as an anti-inflammatory, anticonvulsant, antioxidant, antiemetic, anxiolytic, and antipsychotic agent. As a result, CBD is a potential medication for the treatment of neuroinflammation, epilepsy, oxidative injury, vomiting and nausea, anxiety, and schizophrenia. In trials on animals, it was found to assist in reducing discomfort.

Is It Safe To Take CBD And Viagra Together?

You may have heard that CBD can be used to treat a variety of ailments, but did you know that it can also be used in conjunction with other medications? That’s right, CBD can be stacked with other drugs to amplify their effects. But is it safe to take CBD and Viagra together?

It turns out that you can, but there can be a mild interaction between the two, so you’ll want to approach the combination with caution. The two substances work by different mechanisms, so they do not interact adversely with each other in serious ways, but you still want to use caution.

When combined, there is a chance that they will work synergistically, enhancing the benefits of both substances. Plus, because both substances act as vasodilators (drugs that expand blood vessels), taking them together has been shown to improve erectile function by increasing blood flow to the penis.

As always, consult your doctor before starting any new medication regimen or treatment plan. Although stacking CBD and viagra together is generally considered safe, you’ll always want to be aware of the possible interactions between each.

For example, because both treatments are vasodilators, taking them together could lead to dangerously low blood pressure if taken concurrently with alpha-blockers such as Hytrin® or Flomax®. If you are on these medications already, speak to your doctor about potential interactions before adding CBD into the mix.

Effects Of Taking Both

Although it’s generally safe to take both CBD and Viagra, they each have different effects. CBD may help reduce anxiety and stress, while Viagra is used to treat erectile dysfunction. When taken together, you may experience increased relaxation and improved sexual function.

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There are some reports that the combination of the two can increase plasma levels in the body, especially if you’re taking Viagra on a daily basis.

However, it’s important to remember that everyone reacts differently to these substances, so be sure to start with a low dose and increase gradually as needed. Some people are more sensitive to the effects of drugs than others, and taking too much could lead to feelings of over-sedation or nausea.

In addition to Viagra, if you’re currently taking medication for a mental health condition such as depression or anxiety, speak with your doctor before mixing cannabis or any other substances with your prescription medications. It’s also worth noting that there are possible interactions between cannabis and certain medications such as blood thinners (anti-coagulants), clozapine (an antipsychotic), proton pump inhibitors (PPIs), and serotonin reuptake inhibitors (SSRIs).

While this blog post has touched on some of the most common questions about combining CBD and viagra, there are many variables that come into play when considering whether or not it is appropriate for you. Consult with your physician if you have any concerns about mixing the two in order to find out what would work best for you.

Viagra Side Effects

Viagra can cause a number of side effects, including headaches, indigestion, flushed skin, and changes in vision. It can also cause more serious side effects like chest pain, irregular heartbeat, and fainting. If you experience any of these potential side effects of Viagra, you’ll want to immediately stop taking the medication and call your doctor.

CBD is known to cause dry mouth, lethargy, and alterations in appetite. It can also interact with other medications you’re taking, so it’s important to talk to your doctor before using CBD to make 100% sure. CBD can cause increased sleepiness when taken in combination with caffeine or alcohol.

The effect of CBD on this medication isn’t entirely clear yet, and more studies need to be conducted. There haven’t been enough studies to determine the full extent of how much CBD interacts with Viagra or how these two drugs might work together.

If you’re on the fence about trying out the combination of these two products, you may want to avoid mixing these two medications, especially if you have an underlying heart condition because the combination could have dangerous effects on your heart rate and blood pressure levels.

Is It Possible To Overdose On Both?

It’s possible, but it would be very difficult to do so. The lethal dose of CBD is around 20,000 times the average dose, while the lethal dose of Viagra is only around four times the average dose. So, you would need to take a lot of both drugs to reach a lethal level. However, it’s important to remember that everyone reacts differently to medications, so it’s always best to speak with a doctor before starting any new medication regimen. What Are Some Potential Side Effects?:

It is important to remember that if one has taken more than the recommended dose of either drug, that emergency medical attention should be considered immediately. In addition to having an increased risk of overdose due to taking more than the recommended dosage of either drug on their own, there is also an increased risk if one has taken more than the recommended dosage of both drugs at once.

What Are The Side Effects Of CBD?

CBD can counter the psychoactive effects of THC and help with anxiety and stress. There are, however, a few side effects that may occur.

Mild nausea: Some people report feeling nauseous after taking CBD oil. This is likely due to the way your body metabolizes the cannabinoids; if you experience this effect, try taking CBD with food or another fatty meal.

Changes in blood pressure: Some users have reported an increase in blood pressure after taking CBD oil. If you already have high blood pressure or are concerned about your blood pressure increasing, be sure to speak with your doctor before starting a new supplement regimen with CBD oil.

Diarrhea: Diarrhea is another common side effect of CBD oil use. It’s important to note that diarrhea can be caused by many other factors besides using a supplement like CBD oil; if you’re experiencing diarrhea after taking this supplement it may not be related at all! Additionally, some research has shown that cannabis has an anti-diarrheal effect in some cases so keep this in mind if you experience diarrhea after taking it for the first time!

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CBD is known to cause drowsiness and sleepiness. It can also interact with other medications you’re taking, like blood thinners. In high doses, CBD can cause liver damage. Some people also experience dry mouth, low blood pressure, and lightheadedness. CBD can also affect your appetite. If you’re thinking about using CBD, be sure to talk to your doctor first.

Final Thoughts

Despite the need for more research, it seems generally safe to combine CBD with Viagra. You should always see your doctor before taking any medicine, including natural ones like CBD, as it might slow the metabolism and occasionally raise the chance of Viagra’s adverse effects.

Start with a modest dose and gradually raise it as needed because combining the two substances may intensify their effects. Always be sure to get top-notch products from reputable suppliers.

Does CBD Interact With Sildenafil (Viagra)?

Cannabidiol or CBD may prolong the effects of sildenafil (Viagra) — but is this combination safe? What are the risks?

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Sildenafil (Viagra) is used in the treatment of erectile dysfunction (ED).

Cannabidiol (AKA CBD) is primarily used to manage chronic pain, anxiety, or insomnia — but it has many other health benefits as well.

Some people report using CBD alongside sildenafil to boost its effects — helping to increase erectile function and eliminate concomitant issues like performance anxiety.

Is this combination safe? What are the risks of taking CBD with Viagra (sildenafil)?

Table of Contents

Does CBD Interact With Sildenafil (Viagra)?

Yes. CBD can interact with sildenafil (Viagra) and should be used with caution.

The main concern with using CBD and Viagra is an increased risk of side effects. While uncommon, Viagra can lead to headaches, dizziness, indigestion, and a condition called priapism which involves painful and long-lasting erections.

CBD may also prolong the effects of Viagra by slowing down the body’s ability to eliminate it.

Let’s explore each type of interaction more closely.

A) Slowed Elimination (Metabolic Inhibition)

Drug metabolism occurs in the body due to the effects of a group of enzymes from the P450 family. Metabolic inhibition occurs when two drugs need the same enzymes to get metabolized. Hence, they end up competing against each other for the said enzymes. This action could result in slowing down the metabolism of one or both drugs.

Sildenafil is extensively metabolized by CYP450 enzymes, especially CYP3A4 (major route) and CYP2C9 (minor route). CBD also gets metabolized by these same enzymes.

Because of this ability, if CBD and sildenafil are taken together, the plasma levels of sildenafil can rise in the body. This only becomes dangerous if Viagra is used continuously on a daily basis. Over time, concentrations of the drug can build up to dangerous levels. It’s important to allow enough time between doses for it to be cleared from the body.

B) Increased Effect (Agonistic Interaction)

An agonistic interaction occurs when two or more items exhibit the same effect on the body.

In the case of CBD and sildenafil, the shared effect focuses on blood vessel dilation. Both CBD and sildenafil cause the blood vessels to relax. This could lead to symptoms of excessive relaxation, which include dizziness, headaches, and priapism.

Other Names For Sildenafil(Viagra)

Sildenafil is sold under many different names. All share the same risk and potential interactions.

Other names for sildenafil include:

  • Alsigra
  • Aryagra
  • Caverta
  • Edegra
  • Giagra
  • Medigra
  • Penegra
  • Revatio
  • Silagra
  • Vega
  • Vizarsin
  • Xcite
  • Zenegra

Similar Medications: CBD & Erectile Dysfunction Medications

CBD and erectile dysfunction medications (PDE5 inhibitors) all carry the same level of risk for interaction. Most ED medications work through the same mechanism and require metabolism by the same enzymes in the liver.

Here’s a list of similar medications that share a similar level of risk when combined with CBD:

Is It Safe to Take CBD & Sildenafil (Viagra) Together?

The interaction between sildenafil and CBD is considered mild.

However, because of the severity of one side effect in particular (priapism), it’s wise to speak to your doctor before taking CBD alongside your prescription Viagra.

To further reduce your chances of experiencing interactions, it’s wise to separate the doses of each substance by about 2 hours.

If you experience any problems or concerns, contact your physician immediately.

Is CBD A Viable Alternative to Sildenafil (Viagra)?

CBD is not considered a viable alternative to sildenafil.

Cannabidiol and other cannabinoids have been shown to improve ED in some individuals, but this effect relies more heavily on the effects of CBD for reducing anxiety conditions (such as performance anxiety).

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Sildenafil targets the blood vessels directly feeding blood flow to the penis. This effect is not found in studies exploring the effects of CBD.

For people who may be experiencing mild forms of ED or could trace the cause of their ED to anxiety, CBD could be a safer alternative. However, people who experience ED as a result of mechanical dysfunctions are unlikely to find CBD even remotely as effective for managing symptoms as sildenafil.

What is Sildenafil (Viagra)?

Sildenafil is a phosphodiesterase type 5 (PDE5) inhibitor. Viagra is one of its brand names. It’s used in the treatment of erectile dysfunction and pulmonary hypertension.

It is an FDA-approved drug and is sold as a prescription-only drug in most countries.

Sildenafil (Viagra) Specs:

Drug Name Sildenafil
Trade Names Viagra, Silagra, Alsigra, Aryagra, Caverta, Edegra, Giagra, Medigra, Penegra, Vega, Xcite, Zenegra, Revatio, Vizarsin
Classification Phosphodiesterase 5 inhibitor
CYP Metabolism CYP450 enzymes, especially CYP450 3A4(major route) and CYP2C9 (minor route)
Interaction With CBD Metabolic inhibitor, Agonistic
Risk of Interaction Mild

What Does Sildenafil (Viagra) Do?

Sildenafil works by inhibiting phosphodiesterase 5 (PDE5). Its main action is to increase the blood flow to a flaccid penis. This ability causes it to get erect. Sildenafil does this by inhibiting an enzyme called phosphodiesterase type 5 (PDE5). PDE5 is commonly found in corpora cavernosa, vascular smooth muscles, visceral smooth muscles, and platelets.

Originally developed as a potential blood pressure medication, sildenafil’s ability to cause erection in patients with erectile dysfunction was accidental but a very welcome one. This discovery caused it to become one of the most valuable methods to treat ED.

Generally, in sexual intercourse, after an adequate amount of foreplay, there will be a release of nitric oxide (NO) from nerve terminals and endothelial cells. This action releases cyclic guanosine monophosphate (cGMP) too.

The cGMP’s release causes the muscles of corpora cavernosa in the penis to relax and the blood vessels to get dilated. It leads to a rapid entry of blood into those vessels, causing the penis to engorge, grow large, and get erect. The penis stays so until the end of the intercourse and until after ejaculation occurs.

The enzyme PDE5 prevents blood vessels in the penis from relaxing. It does this by causing the degradation of cGMP. In most ED patients, the blood vessels in the penis are also affected and lose their ability to relax properly or have some obstructions in them.

Sildenafil inhibits PDE5, increases the level of cGMP in the corpus cavernosum, allows more blood to flow into the penis, and causes the penis to get erect long enough to have sex.

However, sildenafil needs proper sexual stimulation to do its work. With a relaxed mind and good sexual stimulation, this drug may work even better.

Apart from the presence of PDE5 in the corpus cavernosum of the penis, PDE5 is also present in the pulmonary vasculature. Hence, sildenafil can increase cGMP within pulmonary vascular smooth muscle cells and cause them to relax. In patients with pulmonary arterial hypertension, this can lead to vasodilation of the pulmonary vascular bed and systemic circulation.

It is not recommended for use in women and children. Sildenafil does not cause dependence and addiction. This drug may show mild to dangerous interactions when combined with some medications. These include nitrates, antihypertensive medications, guanylate cyclase stimulators, antacids, CYP3A4 inhibitors, and CYP3A4 inducers. Sildenafil should not be used with these medications.

Sildenafil is not recommended for consumption alongside alcohol of any form. It must be avoided in users with severe heart disease, hypersensitivity to sildenafil, priapism, severe renal and liver disease, stomach ulcers, retinitis pigmentosa, and blood disorders.

Side Effects of Sildenafil (Viagra)

  • Headaches
  • Tingling sensation in the limbs and extremities
  • Hot flushes
  • Abdominal pain
  • Bluish tinted vision
  • Loss of vision
  • Sensitivity to light
  • Nasal blockage
  • Back pain
  • Nausea
  • Abnormal vision
  • Skin rash
  • Dyspepsia
  • Diarrhea
  • Muscle pain
  • Prolonged and painful erection

Key Takeaways: Is it Safe to Take Sildenafil (Viagra) With CBD?

CBD can slow down the metabolism of sildenafil in the body — potentially causing it to remain active in the body for a longer duration.

Additionally, CBD may potentiate some of the effects of Viagra, leading to a higher risk of side effects (especially dizziness and priapism).

Always consult with your doctor before taking CBD if you’ve been given a prescription for Viagra or another version of sildenafil (the active ingredient in Viagra).

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